Orringer M B, Sloan H
Ann Thorac Surg. 1978 Oct;26(4):364-74. doi: 10.1016/s0003-4975(10)62905-0.
Acute monilial esophagitis generally responds well to oral nystatin therapy, and long-term sequelae of this condition have not been well recognized. Nor is it generally appreciated that Candida infections of the esophagus may occur in subacute or chronic form. Four men, 34, 40, 41, and 49 years old, have been treated for esophageal stenoses resulting from different types of chronic monilial esophageal involvement. All were seen with painless dysphagia and strictures of the upper half of the thoracic esophagus. In 2 patients, an associated roentgenographic pattern of "intramural esophageal pseudodiverticulosis" was present. Two patients have been treated successfully with esophageal dilation, 1 required substernal colonic bypass of the stenotic, perforated esophagus, and 1 is being evaluated for esophageal bypass. Esophageal moniliasis must be considered in the differential diagnosis of benign esophageal strictures, particularly those involving the upper half of the thoracic esophagus.
急性念珠菌性食管炎通常对口服制霉菌素治疗反应良好，而且这种疾病的长期后遗症尚未得到充分认识。食管念珠菌感染可能以亚急性或慢性形式发生，这一点也未得到普遍重视。4名年龄分别为34岁、40岁、41岁和49岁的男性因不同类型的慢性念珠菌性食管受累导致食管狭窄而接受治疗。所有患者均表现为无痛性吞咽困难和胸段食管上半段狭窄。2例患者伴有“食管壁内假性憩室病”的X线表现。2例患者经食管扩张治疗成功，1例因狭窄、穿孔的食管需要行胸骨后结肠旁路手术，1例正在评估是否行食管旁路手术。在良性食管狭窄的鉴别诊断中，尤其是涉及胸段食管上半段的狭窄，必须考虑食管念珠菌病。
