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环形心内膜心室切开术:一种治疗心肌梗死后药物治疗无效的危及生命的室性心动过速的新手术方法。

Encircling endocardial ventriculotomy: a new surgical treatment for life-threatening ventricular tachycardias resistant to medical treatment following myocardial infarction.

作者信息

Guiraudon G, Fontaine G, Frank R, Escande G, Etievent P, Cabrol C

出版信息

Ann Thorac Surg. 1978 Nov;26(5):438-44. doi: 10.1016/s0003-4975(10)62923-2.

Abstract

Ventricular tachycardias occurring after myocardial infarction (MI) and resistant to medical treatment were successfully treated in 5 patients by encircling endocardial ventriculotomy. All patients had a history of MI. The delay between MI and ventricular tachycardias ranged from 1 month to 8 years. A reentrant mechanism was demonstrated by laboratory studies. Under cardiopulmonary bypass, the left ventricle was entered through the thin fribrous scar. Encircling endocardial ventriculotomy was carried out from the inside of the ventricle, through the whole thickness of the normal myocardium, and along the border of the endocardial fibrosis, which delineated the area of diseased myocardium. The ventriculotomy was placed in the free wall or in the septum or in both of these locations. It was repaired and the left ventricle was closed. Drug therapy was discontinued after operation. No ventricular tachycardias recurred during a follow-up period of 6 to 24 months. The effectiveness of encircling endocardial ventriculotomy is explained by the exclusion of the entire diseased area, especially the border zone and the septum. This technique is useful in any location of MI.

摘要

5例心肌梗死(MI)后发生且药物治疗无效的室性心动过速患者通过心内膜环形心室切开术成功治愈。所有患者均有MI病史。MI与室性心动过速之间的间隔时间为1个月至8年。实验室研究证实存在折返机制。在体外循环下,通过薄纤维瘢痕进入左心室。从心室内侧开始,穿过正常心肌的全层,沿着心内膜纤维化边界进行心内膜环形心室切开术,该边界划定了病变心肌区域。心室切开术位于游离壁、室间隔或这两个部位。进行修复并关闭左心室。术后停用药物治疗。在6至24个月的随访期内未再发生室性心动过速。心内膜环形心室切开术的有效性是通过排除整个病变区域,尤其是边界区和室间隔来解释的。该技术在MI的任何部位都有用。

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