Caeiro J L, Liste I, Vogt U, Ribeiro J C
Departmento de Antropoloxía, Facultade de Bioloxía, Universidade de Santiago de Compostela, Galicia, Spain.
Electrophoresis. 1994 Aug-Sep;15(8-9):1191-2. doi: 10.1002/elps.11501501179.
Inter-alpha-trypsin inhibitor (ITI) phenotypes were classified in the West African population of Cabo Verde by polyacrylamide gel isoelectric focusing, followed by immunofixation and silver staining. Gene frequencies of the alleles ITI1, ITI2, ITI3, and ITI4 were calculated to be 0.532, 0.153, 0.307 and 0.002, respectively. A new rare allele, ITI7, was found, providing evidence for further genetic variability of the ITI protein. The ITI7 allele frequency has been determined to 0.006. The assumption that allele ITI*3 may be used to characterize populations of African origin is supported by our data.
通过聚丙烯酰胺凝胶等电聚焦，随后进行免疫固定和银染，对佛得角的西非人群中的α-胰蛋白酶抑制剂（ITI）表型进行了分类。等位基因ITI1、ITI2、ITI3和ITI4的基因频率经计算分别为0.532、0.153、0.307和0.002。发现了一个新的罕见等位基因ITI7，为ITI蛋白的进一步遗传变异性提供了证据。已确定ITI7等位基因频率为0.006。我们的数据支持等位基因ITI*3可用于表征非洲裔人群的假设。
