Kadota O, Sakaki S, Kumon Y, Ohta S, Kohno K
Department of Neurological Surgery, Ehime University School of Medicine.
Neurol Med Chir (Tokyo). 1994 Nov;34(11):768-72. doi: 10.2176/nmc.34.768.
A 40-year-old female presented with gait disturbance and dysarthria. Computed tomography revealed a large cystic tumor in the cerebellar vermis with a mural nodule located in the deepest portion of the cyst. The magnetic resonance (MR) imaging appearance suggested cavernous angioma. The solid nodule was completely removed through the suboccipital approach. The cyst was filled with transparent yellowish fluid which showed positive Froin's sign. The histological diagnosis of the mural nodule was cavernous angioma. The cyst wall consisted of gliosis and contained no angiomatous tissues. Postoperative MR imaging demonstrated that the nodule was totally removed and the cyst size was reduced. The neurological deficits improved postoperatively. The mechanism of formation of the large cyst was assumed to be repeated peritumoral hemorrhage.
一名40岁女性出现步态障碍和构音障碍。计算机断层扫描显示小脑蚓部有一个大的囊性肿瘤,囊壁结节位于囊肿最深部。磁共振成像表现提示海绵状血管瘤。通过枕下入路将实性结节完全切除。囊肿内充满透明淡黄色液体,显示弗洛因征阳性。囊壁结节的组织学诊断为海绵状血管瘤。囊肿壁由胶质增生组成,不含血管瘤组织。术后磁共振成像显示结节已完全切除,囊肿大小缩小。术后神经功能缺损有所改善。大囊肿的形成机制推测为肿瘤周围反复出血。