Blot W J, Devesa S S, McLaughlin J K, Fraumeni J F
Epidemiology and Biostatistics Program, National Cancer Institute, Bethesda, Maryland 20892.
Cancer Surv. 1994;19-20:23-42.
Trends for oral and pharyngeal cancers vary by anatomical subsite. For tumours of the tongue, mouth and pharynx (excluding nasopharynx), rates are rising in many areas of the world, particularly in Europe, at least in part attributable to rising alcohol consumption. Exceptions to this pattern occur in the USA, where incidence and mortality among whites are falling. There are mild downward trends in the incidence of lip, salivary gland and nasopharyngeal cancers, which (except for nasopharyngeal cancer among southern Chinese) occur at much lower frequency. The trends provide interesting clues to the causes of these cancers whose aetiology is partially but not fully understood.
口腔癌和咽癌的发病趋势因解剖亚部位而异。对于舌、口腔和咽（不包括鼻咽）的肿瘤，世界上许多地区的发病率都在上升，尤其是在欧洲，至少部分归因于酒精消费量的增加。美国是这种模式的例外，白人的发病率和死亡率正在下降。唇癌、唾液腺癌和鼻咽癌的发病率呈轻微下降趋势，这些癌症（中国南方鼻咽癌除外）的发病频率要低得多。这些趋势为这些病因部分但尚未完全明确的癌症的病因提供了有趣的线索。
