Warny M, Denie C, Delmée M, Lefebvre C
Département de Microbiologie, Université Catholique de Louvain, Bruxelles, Belgique.
Acta Clin Belg. 1995;50(1):36-9. doi: 10.1080/17843286.1995.11718419.
A 53-year-old woman suffered six episodes of Clostridium difficile-pseudomembranous colitis. The serological follow-up demonstrated the absence of a rise in IgG and IgA to toxin A. Human pooled gamma globulin was administered during the fifth relapse and raised IgG levels to toxin A. Normal stools reappeared a week later. The role of the antibodies to toxin A and gamma globulin in C. difficile colitis are discussed.
一名53岁女性患艰难梭菌假膜性结肠炎6次。血清学随访显示，针对毒素A的IgG和IgA未升高。在第五次复发期间给予人混合丙种球蛋白，使针对毒素A的IgG水平升高。一周后再次出现正常粪便。讨论了针对毒素A的抗体和丙种球蛋白在艰难梭菌结肠炎中的作用。
