Ibba-Manneschi L, Martini M, Zecchi-Orlandini S, Faussone-Pellegrini M S
Department of Human Anatomy and Histology, University of Florence, Italy.
Histol Histopathol. 1995 Jan;10(1):17-25.
The organization of the Enteric Nervous System (ENS) was studied in the human colon. Fragments of the whole colonic wall were either routinely processed or Zinc-Iodide Osmium impregnated. Single-layer preparations were also obtained from some of the Zinc-Iodide Osmium-impregnated specimens. The results showed some differences in the organization of human colonic ENS from that of other mammals. In fact, the human submucous plexus was made up of three interconnected ganglionated networks arranged along three different planes. With respect to the myenteric plexus, its ganglia were large sized and irregularly shaped. Moreover, during the microdissection of the colonic wall, we found the absence of a cleavage plane between the circular and longitudinal muscle layers; on the other hand the cleavage plane between mucosa and submucosa was not immediately below the muscularis mucosae, but slightly deeper, since the innermost part of the submucosa remained adhering to overlying layers.
对人类结肠中的肠神经系统（ENS）结构进行了研究。完整结肠壁的片段要么进行常规处理，要么用碘化锌锇进行浸染。还从一些用碘化锌锇浸染的标本中获得了单层制剂。结果显示，人类结肠ENS的结构与其他哺乳动物的存在一些差异。事实上，人类黏膜下神经丛由沿着三个不同平面排列的三个相互连接的神经节网络组成。关于肌间神经丛，其神经节体积大且形状不规则。此外，在结肠壁的显微解剖过程中，我们发现环形肌层和纵行肌层之间不存在分裂平面；另一方面，黏膜和黏膜下层之间的分裂平面并不直接在黏膜肌层下方，而是稍深一些，因为黏膜下层的最内层仍与上层粘连。
