Höfner K, Kramer A E, Tan H K, Krah H, Jonas U
Department of Urology, Hannover Medical School, Germany.
World J Urol. 1995;13(1):59-64. doi: 10.1007/BF00182667.
The present discussion on the natural history, growth rate pathophysiology, morbidity, and possible treatment of benign prostatic hyperplasia (BPH) reinforces the need to objectify mechanical BPH-induced obstruction with pressure-flow study. Different methods for the quantification of BPH-induced obstruction exist and the grade of simplification depends on their working mechanism. To review the limitations of the current concepts, 118 BPH patients were selected for computerized pressure-flow data analysis according to quadratic passive urethral resistance relation (PURR) function. The CHESS classification differs from all other concepts due to its two-dimensional character and was developed as a result of the following way of thinking: (1) the whole individual pressure-flow plot is the most accurate basis for further analysis; (2) PURR as the true low-pressure flank of the individual plot is the most favorable definition for mechanical obstruction; (3) PURR quantification requires at least two parameters, footpoint and curvature/slope, with regard to the documented missing significant correlation of both; and (4) a two-parameter-based classification is two-dimensional (CHESS classification).
当前关于良性前列腺增生（BPH）的自然病史、生长速率病理生理学、发病率及可能的治疗方法的讨论，强化了通过压力 - 流量研究客观化机械性BPH所致梗阻的必要性。存在多种量化BPH所致梗阻的方法，其简化程度取决于工作机制。为审视当前概念的局限性，根据二次被动尿道阻力关系（PURR）函数，选择118例BPH患者进行计算机化压力 - 流量数据分析。CHESS分类因其二维特性与所有其他概念不同，它是通过以下思维方式发展而来的：（1）整个个体压力 - 流量图是进一步分析的最准确基础；（2）PURR作为个体图真正的低压侧翼，是机械性梗阻最有利的定义；（3）PURR量化至少需要两个参数，即起点和曲率/斜率，鉴于两者记录的相关性缺乏显著性；（4）基于双参数的分类是二维的（CHESS分类）。
