The effects of elevated glucose levels on the incorporation of glucose and acetate into aortic lipids of the dog.

The effect of elevated glucose concentration on the incorporation of labeled glucose and acetate into aortic lipids of the dog was studied. Increased medium glucose concentration (80 mg p. 100-300 mg p. 100) resulted in: 1. an increased incorporation of glucose into aortic total lipids, phospholipids and triglycerides; 2. an increased incorporation of acetate into each lipid fraction studied. In addition, the effect of insulin on glucose incorporation into aortic lipid was assessed. At a concentration of 100 mU/ml, insulin had no effect on glucose incorporation into aortic lipids of the dog.