Distinct roles for CD28 and cytotoxic T lymphocyte-associated molecule-4 receptors during T cell activation?
作者信息
Linsley P S
机构信息
Bristol-Myers Squibb Pharmaceutical Research Institute, Seattle, Washington 98121, USA.
出版信息
J Exp Med. 1995 Aug 1;182(2):289-92. doi: 10.1084/jem.182.2.289.
Abstract
摘要
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Distinct roles for CD28 and cytotoxic T lymphocyte-associated molecule-4 receptors during T cell activation?CD28和细胞毒性T淋巴细胞相关分子-4受体在T细胞活化过程中的不同作用？
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本文引用的文献
1
The cytoplasmic domain of CD28 is both necessary and sufficient for costimulation of interleukin-2 secretion and association with phosphatidylinositol 3'-kinase.CD28的胞质结构域对于共刺激白细胞介素-2的分泌以及与磷脂酰肌醇3'-激酶的结合而言，既是必要的也是充分的。
Mol Cell Biol. 1994 May;14(5):3392-402. doi: 10.1128/mcb.14.5.3392-3402.1994.
2
Two-step TCR zeta/CD3-CD4 and CD28 signaling in T cells: SH2/SH3 domains, protein-tyrosine and lipid kinases.T细胞中两步TCR ζ/CD3 - CD4和CD28信号传导：SH2/SH3结构域、蛋白酪氨酸激酶和脂质激酶
Immunol Today. 1994 May;15(5):225-34. doi: 10.1016/0167-5699(94)90248-8.
3
CTLA-4 can function as a negative regulator of T cell activation.细胞毒性T淋巴细胞相关抗原4（CTLA-4）可作为T细胞活化的负调节因子发挥作用。
Immunity. 1994 Aug;1(5):405-13. doi: 10.1016/1074-7613(94)90071-x.
4
CTLA4 mediates antigen-specific apoptosis of human T cells.细胞毒性T淋巴细胞相关抗原4介导人T细胞的抗原特异性凋亡。
Proc Natl Acad Sci U S A. 1995 Jan 31;92(3):811-5. doi: 10.1073/pnas.92.3.811.
5
CTLA-4 binding to the lipid kinase phosphatidylinositol 3-kinase in T cells.细胞毒性T淋巴细胞相关抗原4（CTLA-4）与T细胞中的脂质激酶磷脂酰肌醇3激酶结合。
J Exp Med. 1995 Jan 1;181(1):351-5. doi: 10.1084/jem.181.1.351.
6
Differential T cell costimulatory requirements in CD28-deficient mice.CD28缺陷小鼠中不同的T细胞共刺激需求。
Science. 1993 Jul 30;261(5121):609-12. doi: 10.1126/science.7688139.
7
Absence of B7-dependent responses in CD28-deficient mice.CD28基因缺陷小鼠中缺乏B7依赖性反应。
Immunity. 1994 Sep;1(6):501-8. doi: 10.1016/1074-7613(94)90092-2.
8
9
Treatment of murine lupus with CTLA4Ig.用CTLA4Ig治疗小鼠狼疮。
Science. 1994 Aug 26;265(5176):1225-7. doi: 10.1126/science.7520604.
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