毒红菇急性中毒（作者译）
[Acute poisoning by Gyromitra esculenta (author's transl)].
作者信息
Garnier R, Conso F, Efthymiou M L, Riboulet G, Gaultier M
出版信息
Toxicol Eur Res. 1978 Nov;1(6):359-64.
PMID:754347
Abstract
This kind of poisoning is scarce in France, on the contrary it is most frequent in Eastern Europe. Clinical picture associating cytolytic hepatitis, seizures, and hemolysis reminds us intoxication by hydrazine. In fact there is some evidence that the toxin of this mushroom--called gyromitrin--is transformed in the stomach in methylhydrazine. The mechanism of hepatotoxicity of the later can be compared with that of the metabolites of isoniazid.
摘要
这种中毒现象在法国很少见，相反，在东欧最为常见。伴有细胞溶解性肝炎、癫痫发作和溶血的临床症状让我们联想到肼中毒。事实上，有证据表明这种蘑菇的毒素——即鹿花菌素——在胃中会转化为甲基肼。后者的肝毒性机制可与异烟肼的代谢产物相比较。
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