Batsakis J G, Ro J Y, Frauenhoffer E E
Department of Pathology, University of Texas M. D. Anderson Cancer Center, Houston, USA.
Ann Otol Rhinol Laryngol. 1995 Aug;104(8):668-72. doi: 10.1177/000348949510400815.
The acquired immunodeficiency syndrome and other causes of immunosuppression have ushered in a variety of opportunistic infections. One of these is bacillary angiomatosis, a vasoproliferative lesion whose principal causative agent is Rochalimaea henselae. Bacillary angiomatosis, while preponderantly a cutaneous affliction, can be systemic, including involvement of the head and neck mucous membranes. Molecular technology and epidemiologic studies used to identify the bacterial agent of bacillary angiomatosis have also uncovered R henselae as the organism responsible for most cases of cat-scratch disease. Why the same organism promotes two different histopathologic lesions, as seen in bacillary angiomatosis and cat-scratch disease, is unknown.
获得性免疫缺陷综合征及其他免疫抑制病因引发了多种机会性感染。其中之一是杆菌性血管瘤病,这是一种血管增生性病变,其主要病原体是汉赛巴尔通体。杆菌性血管瘤病虽然主要是一种皮肤疾病,但也可能累及全身,包括头颈部黏膜。用于鉴定杆菌性血管瘤病病原体的分子技术和流行病学研究还发现,汉赛巴尔通体是大多数猫抓病病例的致病原。为何同一病原体能引发杆菌性血管瘤病和猫抓病这两种不同的组织病理学病变,目前尚不清楚。