肿瘤血管系统——一个潜在的治疗靶点。
Tumour vasculature--a potential therapeutic target.
作者信息
Baillie C T, Winslet M C, Bradley N J
机构信息
University Department of Surgery, Royal Free Hospital and School of Medicine, London, UK.
出版信息
Br J Cancer. 1995 Aug;72(2):257-67. doi: 10.1038/bjc.1995.323.
Abstract
The tumour vasculature is vital for the establishment, growth and metastasis of solid tumours. Its physiological properties limit the effectiveness of conventional anti-cancer strategies. Therapeutic approaches directed at the tumour vasculature are reviewed, suggesting the potential of anti-angiogenesis and the targeting of vascular proliferation antigens as cancer treatments.
摘要
肿瘤血管系统对于实体瘤的形成、生长和转移至关重要。其生理特性限制了传统抗癌策略的有效性。本文综述了针对肿瘤血管系统的治疗方法，提示抗血管生成及靶向血管增殖抗原作为癌症治疗手段的潜力。
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