Hoekzema R, Hulsebosch H J, Bos J D
Department of Dermatology, Academisch Medisch Centrum, University of Amsterdam, The Netherlands.
Br J Dermatol. 1995 Aug;133(2):294-9. doi: 10.1111/j.1365-2133.1995.tb02632.x.
We report a 75-year-old man with a fulminant rosacea-like eruption, suggestive of demodicidosis. Multiple Demodex folliculorum mites were found in facial scales and pustules and, on histological examination, in the infundibulum of pilosebaceous follicles and in the dermis. Intradermal mites were surrounded either by polymorphonuclear granulocytes and histiocytes, or by a granulomatous infiltrate containing foreign-body giant cells, which had phagocytosed the parasites. Complete recovery, with disappearance of facial mites, was achieved by treatment with a combination of oral and topical metronidazole, although this drug is not known to be miticidal.
我们报告了一名75岁男性，患有暴发性酒渣鼻样皮疹，提示蠕形螨病。在面部鳞屑和脓疱中发现了多个毛囊蠕形螨，组织学检查显示在皮脂腺毛囊漏斗部和真皮中也有发现。皮内螨被多形核粒细胞和组织细胞包围，或被含有吞噬了寄生虫的异物巨细胞的肉芽肿性浸润所包围。尽管甲硝唑并非已知的杀螨剂，但通过口服和外用甲硝唑联合治疗，面部螨虫消失，患者完全康复。
