Newman E B, Kapoor V, Potter R
J Bacteriol. 1976 Jun;126(3):1245-9. doi: 10.1128/jb.126.3.1245-1249.1976.
The enzyme L-threonine dehydrogenase was demonstrated in extracts of Escherichia coli K-12, and was shown to be the first enzyme of the pathway converting threonine to glycine. The enzyme was induced by L-leucine, but not by its substrate, L-threonine. The metabolic significance of leucine as a catabolic signal for amino acid degradation is considered.
在大肠杆菌K-12提取物中证实了L-苏氨酸脱氢酶,它是将苏氨酸转化为甘氨酸途径中的首个酶。该酶由L-亮氨酸诱导产生,而非由其底物L-苏氨酸诱导。文中考虑了亮氨酸作为氨基酸分解代谢信号的代谢意义。