Shaw T J, Murphy C R
Department of Anatomy and Histology, University of Sydney, NSW, Australia.
Cell Biol Int. 1995 Jul;19(7):577-84. doi: 10.1006/cbir.1995.1104.
Intra-uterine injection of the lectin Concanavalin A (ConA) on day 5 of PSP induced a rapid and persistent infiltration of leucocytes into the rat uterine stroma. Although the infiltration of leucocytes was witnessed along the entire length of the uterine horn, areas of stromal oedema, indicative of decidualisation (as indicated by the positive Pontamine Sky Blue reaction), were only associated with regions in which the movement of leucocytes across the uterine epithelium was evident. Epithelial disruption and trauma was frequently noted within these regions. We believe that ConA may initiate decidualisation through indirectly causing epithelial trauma.
在假孕第5天向子宫内注射凝集素伴刀豆球蛋白A（ConA），可导致白细胞迅速且持续地浸润到大鼠子宫基质中。尽管在子宫角的整个长度上都观察到了白细胞浸润，但基质水肿区域（以阳性滂胺天蓝反应表明有蜕膜化）仅与白细胞穿过子宫上皮运动明显的区域相关。在这些区域经常发现上皮破坏和损伤。我们认为ConA可能通过间接导致上皮损伤来启动蜕膜化。
