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酒精与高血压

Alcohol and hypertension.

作者信息

Beilin L J

机构信息

Department of Medicine, University of Western Australia, Royal Perth Hospital.

出版信息

Clin Exp Pharmacol Physiol. 1995 Mar;22(3):185-8. doi: 10.1111/j.1440-1681.1995.tb01977.x.

Abstract
  1. Regular alcohol consumption is a significant contributor to the prevalence of hypertension in drinking communities. 2. The effect is additive to that of obesity and is partly reversible over 2-4 weeks with moderation of ethanol intake. 3. In heavy drinkers acute alcohol withdrawal may lead to more blood pressure elevation following an initial depressor response. 4. Heavy drinking is also associated with an increased risk of haemorrhagic stroke and cardiomyopathy. 5. Lighter drinking habits appear to offer significant protection against ischaemic heart deaths and ischaemic strokes. 6. Antihypertensive drug treatment for alcohol related hypertension may mask some of the adverse cardiovascular effects of alcohol. 7. Arguments as to whether alcohol is a cause of essential hypertension are tautological, given the many reversible lifestyle factors now known to contribute to the rise in blood pressure with aging.
摘要
  1. 经常饮酒是饮酒人群中高血压患病率的一个重要促成因素。2. 这种影响与肥胖的影响相加,并且随着乙醇摄入量的适度减少,在2至4周内部分可逆。3. 在重度饮酒者中,急性酒精戒断在最初的降压反应后可能导致血压进一步升高。4. 大量饮酒还与出血性中风和心肌病风险增加有关。5. 较轻的饮酒习惯似乎能显著预防缺血性心脏病死亡和缺血性中风。6. 针对酒精相关性高血压的抗高血压药物治疗可能会掩盖酒精对心血管的一些不良影响。7. 鉴于目前已知许多可逆的生活方式因素会导致血压随年龄增长而升高,关于酒精是否是原发性高血压病因的争论是同义反复的。

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