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酒精与高血压

Alcohol and hypertension.

作者信息

Beilin L J

机构信息

Department of Medicine, University of Western Australia, Royal Perth Hospital.

出版信息

Clin Exp Pharmacol Physiol. 1995 Mar;22(3):185-8. doi: 10.1111/j.1440-1681.1995.tb01977.x.

DOI:10.1111/j.1440-1681.1995.tb01977.x
PMID:7554411
Abstract
  1. Regular alcohol consumption is a significant contributor to the prevalence of hypertension in drinking communities. 2. The effect is additive to that of obesity and is partly reversible over 2-4 weeks with moderation of ethanol intake. 3. In heavy drinkers acute alcohol withdrawal may lead to more blood pressure elevation following an initial depressor response. 4. Heavy drinking is also associated with an increased risk of haemorrhagic stroke and cardiomyopathy. 5. Lighter drinking habits appear to offer significant protection against ischaemic heart deaths and ischaemic strokes. 6. Antihypertensive drug treatment for alcohol related hypertension may mask some of the adverse cardiovascular effects of alcohol. 7. Arguments as to whether alcohol is a cause of essential hypertension are tautological, given the many reversible lifestyle factors now known to contribute to the rise in blood pressure with aging.
摘要
  1. 经常饮酒是饮酒人群中高血压患病率的一个重要促成因素。2. 这种影响与肥胖的影响相加,并且随着乙醇摄入量的适度减少,在2至4周内部分可逆。3. 在重度饮酒者中,急性酒精戒断在最初的降压反应后可能导致血压进一步升高。4. 大量饮酒还与出血性中风和心肌病风险增加有关。5. 较轻的饮酒习惯似乎能显著预防缺血性心脏病死亡和缺血性中风。6. 针对酒精相关性高血压的抗高血压药物治疗可能会掩盖酒精对心血管的一些不良影响。7. 鉴于目前已知许多可逆的生活方式因素会导致血压随年龄增长而升高,关于酒精是否是原发性高血压病因的争论是同义反复的。

相似文献

1
Alcohol and hypertension.酒精与高血压
Clin Exp Pharmacol Physiol. 1995 Mar;22(3):185-8. doi: 10.1111/j.1440-1681.1995.tb01977.x.
2
Alcohol, hypertension and cardiovascular disease--implications for management.
Clin Exp Hypertens. 1993 Nov;15(6):1157-70. doi: 10.3109/10641969309037102.
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Alcohol and hypertension--kill or cure?酒精与高血压——是杀手还是良药?
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Alcohol, hypertension, coronary disease and stroke.酒精、高血压、冠心病和中风。
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Curr Hypertens Rep. 2006 Aug;8(4):338-44. doi: 10.1007/s11906-006-0074-z.
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Epidemiology of alcohol and hypertension.酒精与高血压的流行病学
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Effects of alcohol withdrawal on blood pressure in hypertensive heavy drinkers.酒精戒断对高血压重度饮酒者血压的影响。
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10
Influence of pattern of alcohol intake on blood pressure in regular drinkers: a controlled trial.饮酒模式对经常饮酒者血压的影响:一项对照试验。
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Role of Alcohol Oxidative Metabolism in Its Cardiovascular and Autonomic Effects.酒精氧化代谢在其心血管和自主神经效应中的作用。
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Effect of chronic ethanol exposure on rat ventilatory responses to hypoxia and hypercapnia.慢性乙醇暴露对大鼠低氧和高碳酸血症通气反应的影响。
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Inverse relationship between central serotonergic neurotransmission and blood pressure in alcohol-dependent male subjects.酒精依赖男性受试者中枢5-羟色胺能神经传递与血压之间的负相关关系。
J Neural Transm (Vienna). 2006 Oct;113(10):1511-7. doi: 10.1007/s00702-005-0426-x. Epub 2006 Feb 9.
6
Alcohol and medication interactions.酒精与药物相互作用。
Alcohol Res Health. 1999;23(1):40-54.
7
Antihypertensive effect of low ethanol intake in spontaneously hypertensive rats.低乙醇摄入量对自发性高血压大鼠的降压作用。
Mol Cell Biochem. 1999 Oct;200(1-2):85-92. doi: 10.1023/a:1006950414560.