Chong H H, Plotnick G D
Department of Medicine, University of Maryland School of Medicine, Baltimore, USA.
Compr Ther. 1995 Jul;21(7):378-85.
Pericardial effusions may be present in a variety of clinical situations, often presenting challenging clinical diagnostic and therapeutic problems. Although several imaging modalities are available, ECHO has become the diagnostic method of choice due to its portability and wide availability. CT and MRI may also be employed and may be more accurate. A pericardial effusion under pressure may result in hemodynamic compromise and tamponade. Although there are several echocardiographic clues to tamponade (including diastolic chamber collapse, Doppler flow velocity paradoxus, and inferior vena cava phlethora), the diagnosis remains a clinical and hemodynamic one. The clinical signs include elevated jugular venous pressure, hypotension, tachycardia, and pulsus paradoxus. Hemodynamic measurements include equalization of diastolic pressures and decreased cardiac output Treatment of tamponade involves drainage of the effusion and prevention of reaccumulation. Needle pericardiocentesis via the subxiphoid approach is a reasonable initial treatment. However, this may need to be accompanied by catheter drainage or surgical pericardial window. A new catheter based technique--percutaneous balloon pericardiotomy-- appears useful in select patients with malignancy in order to avoid more invasive surgical procedures. Occasionally, in patients with recurrent effusions, instillation of sclerosing agents into the pericardial space or even total pericardiectomy may be necessary.
心包积液可见于多种临床情况,常常带来具有挑战性的临床诊断和治疗问题。尽管有多种影像学检查方法可供使用,但由于超声心动图(ECHO)具有便携性且应用广泛,已成为首选的诊断方法。CT和MRI也可采用,且可能更为准确。受压的心包积液可能导致血流动力学障碍和心脏压塞。虽然有多种超声心动图提示心脏压塞的线索(包括舒张期心腔塌陷、多普勒血流速度矛盾现象和下腔静脉扩张),但诊断仍基于临床和血流动力学表现。临床体征包括颈静脉压升高、低血压、心动过速和奇脉。血流动力学测量包括舒张压相等和心输出量降低。心脏压塞的治疗包括引流积液并防止其再次积聚。经剑突下途径进行心包穿刺抽液是一种合理的初始治疗方法。然而,这可能需要辅以导管引流或心包开窗手术。一种新的基于导管的技术——经皮球囊心包切开术——对于某些恶性肿瘤患者似乎有用,可避免更具侵入性的外科手术。偶尔,对于反复出现积液的患者,可能需要在心包腔内注入硬化剂甚至进行全心包切除术。