Wyatt J L
Comput Programs Biomed. 1978 Sep;8(3-4):180-95. doi: 10.1016/0010-468x(78)90026-0.
This paper develops the network theory of chemical reaction systems from first principles. The network approach is then used to derive a canonical set of differential equations for reaction--diffusion systems, and an analysis of the Brusselator is presented as an example.