葡萄球菌直接刺激后人腹膜间皮细胞白细胞介素-8的产生
Interleukin-8 production by human mesothelial cells after direct stimulation with staphylococci.
作者信息
Visser C E, Steenbergen J J, Betjes M G, Meijer S, Arisz L, Hoefsmit E C, Krediet R T, Beelen R H
机构信息
Department of Cell Biology & Immunology, Faculty of Medicine, Academic Hospital Vrije Universiteit, Amsterdam, The Netherlands.
出版信息
Infect Immun. 1995 Oct;63(10):4206-9. doi: 10.1128/iai.63.10.4206-4209.1995.
Abstract
Mesothelial cells (MC) are able to produce interleukin-8 (IL-8) after stimulation with IL-1 beta or tumor necrosis factor alpha. The aim of our study was to investigate whether MC are able to produce IL-8 after direct stimulation with clinically relevant bacteria. We observed a significant IL-8 response by the MC which were directly stimulated with viable staphylococci.
摘要
间皮细胞（MC）在受到白细胞介素-1β（IL-1β）或肿瘤坏死因子α刺激后能够产生白细胞介素-8（IL-8）。我们研究的目的是调查间皮细胞在受到临床相关细菌直接刺激后是否能够产生IL-8。我们观察到，受到活葡萄球菌直接刺激的间皮细胞出现了显著的IL-8反应。
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