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英国皮肤恶性黑色素瘤的早期检测

Early detection of cutaneous malignant melanoma in Britain.

作者信息

Melia J

机构信息

DH Cancer Screening Evaluation Unit, Institute of Cancer Research, Sutton, Surrey, UK.

出版信息

Int J Epidemiol. 1995;24 Suppl 1:S39-44. doi: 10.1093/ije/24.supplement_1.s39.

DOI:10.1093/ije/24.supplement_1.s39
PMID:7558550
Abstract

A multidisciplinary approach to research has been one of the hallmarks of Walter Holland's outstanding career in medical research. Studies arising from evaluation of the Cancer Research Campaign's health education programme for the early detection of cutaneous malignant melanoma were reviewed at Walter's Festschrift because they illustrate the importance of the multidisciplinary approach and raise issues about medical screening which has been a special interest of Walter's The programme took place in 1987 in seven areas of England and Scotland with a target population of 3.6 million. The main aim of the evaluation study is to investigate the effect of the programme on mortality from melanoma. Interim effects on awareness about melanoma, workload and incidence rates of melanoma by stage are reviewed. The importance of collaboration between dermatologists, epidemiologists, histopathologists and health education specialists has been essential. However, the effectiveness of high profile campaigns alone to promote early detection of melanoma is uncertain and future initiatives should be evaluated in randomized controlled trials.

摘要

多学科研究方法一直是沃尔特·霍兰德在医学研究领域杰出职业生涯的标志之一。在沃尔特的纪念文集上回顾了对癌症研究运动早期发现皮肤恶性黑色素瘤健康教育项目的评估所产生的研究,因为它们说明了多学科方法的重要性,并提出了关于医学筛查的问题,而医学筛查一直是沃尔特特别感兴趣的领域。该项目于1987年在英格兰和苏格兰的七个地区开展,目标人群为360万。评估研究的主要目的是调查该项目对黑色素瘤死亡率的影响。文中回顾了该项目对黑色素瘤认知、工作量和各阶段黑色素瘤发病率的中期影响。皮肤科医生、流行病学家、组织病理学家和健康教育专家之间的合作至关重要。然而,仅靠备受瞩目的运动来促进黑色素瘤的早期发现的有效性尚不确定,未来的举措应在随机对照试验中进行评估。

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Early detection of cutaneous malignant melanoma in Britain.英国皮肤恶性黑色素瘤的早期检测
Int J Epidemiol. 1995;24 Suppl 1:S39-44. doi: 10.1093/ije/24.supplement_1.s39.
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The relation between mortality from malignant melanoma and early detection in the Cancer Research Campaign Mole Watcher Study.癌症研究运动“痣监测者”研究中恶性黑色素瘤死亡率与早期检测的关系。
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Reducing mortality in individuals at high risk for advanced melanoma through education and screening.通过教育和筛查降低高危黑色素瘤个体的死亡率。
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Evaluation of a Skin Self-Examination Programme: a Four-Stage Recursive Model.一项皮肤自我检查计划的评估:一个四阶段递归模型。
Asian Pac J Cancer Prev. 2017 Apr 1;18(4):1063-1067. doi: 10.22034/APJCP.2017.18.4.1063.
2
Mortality from cutaneous melanoma: evidence for contrasting trends between populations.皮肤黑色素瘤死亡率:不同人群间对比趋势的证据。
Br J Cancer. 2000 Jun;82(11):1887-91. doi: 10.1054/bjoc.1999.1243.
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Feasibility of targeted early detection for melanoma: a population-based screening study.黑色素瘤靶向早期检测的可行性:一项基于人群的筛查研究。
Br J Cancer. 2000 May;82(9):1605-9. doi: 10.1054/bjoc.2000.1183.
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A nationwide survey of observer variation in the diagnosis of thin cutaneous malignant melanoma including the MIN terminology. CRC Melanoma Pathology Panel.一项关于薄皮恶性黑色素瘤诊断中观察者变异的全国性调查,包括MIN术语。结直肠癌黑色素瘤病理小组。
J Clin Pathol. 1997 Mar;50(3):202-5. doi: 10.1136/jcp.50.3.202.