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微小胸腺瘤与重症肌无力

Microscopic thymoma and myasthenia gravis.

作者信息

Puglisi F, Finato N, Mariuzzi L, Marchini C, Floretti G, Beltrami C A

机构信息

University of Udine, Italy.

出版信息

J Clin Pathol. 1995 Jul;48(7):682-3. doi: 10.1136/jcp.48.7.682.

Abstract

A rare case of microscopically sized thymoma is described in a 56 year old man suffering from myasthenia gravis. Histological examination of the surgically removed thymus showed the presence of several epithelial thymoma-like islands. As controls, 100 thymuses obtained from consecutive necropsies were sampled: 4% of these cases showed epithelial islands. This case is further proof that "microscopic thymoma" is a true pathological entity and suggests that every thymus removed from myasthenic patients in which there is no macroscopic evidence of thymoma should be examined microscopically on serial sections.

摘要

本文描述了一例罕见的显微镜下可见大小的胸腺瘤,患者为一名56岁患有重症肌无力的男性。对手术切除的胸腺进行组织学检查,发现存在多个上皮样胸腺瘤样岛状结构。作为对照,从连续尸检中获取100个胸腺进行采样:其中4%的病例显示有上皮岛状结构。该病例进一步证明“显微镜下胸腺瘤”是一种真正的病理实体,并表明对于从无胸腺瘤宏观证据的肌无力患者切除的每一个胸腺,都应在连续切片上进行显微镜检查。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c90b/502727/eba2bf4546f7/jclinpath00232-0088-a.jpg

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