Puglisi F, Finato N, Mariuzzi L, Marchini C, Floretti G, Beltrami C A
University of Udine, Italy.
J Clin Pathol. 1995 Jul;48(7):682-3. doi: 10.1136/jcp.48.7.682.
A rare case of microscopically sized thymoma is described in a 56 year old man suffering from myasthenia gravis. Histological examination of the surgically removed thymus showed the presence of several epithelial thymoma-like islands. As controls, 100 thymuses obtained from consecutive necropsies were sampled: 4% of these cases showed epithelial islands. This case is further proof that "microscopic thymoma" is a true pathological entity and suggests that every thymus removed from myasthenic patients in which there is no macroscopic evidence of thymoma should be examined microscopically on serial sections.
本文描述了一例罕见的显微镜下可见大小的胸腺瘤，患者为一名56岁患有重症肌无力的男性。对手术切除的胸腺进行组织学检查，发现存在多个上皮样胸腺瘤样岛状结构。作为对照，从连续尸检中获取100个胸腺进行采样：其中4%的病例显示有上皮岛状结构。该病例进一步证明“显微镜下胸腺瘤”是一种真正的病理实体，并表明对于从无胸腺瘤宏观证据的肌无力患者切除的每一个胸腺，都应在连续切片上进行显微镜检查。
