[从1129个角膜植片（1982年至1991年）的组织病理学研究看穿透性角膜移植术的适应症]

[Indications of penetrating keratoplasty from a histopathological study of 1129 corneal buttons (from 1982 to 1991)].

作者信息

Leger F, Ndiaye P A, Williamson W, Lagoutte F, Riss I

机构信息

Département d'Anatomie Pathologique, Groupe Hospitalier Pellegrin, Bordeaux.

出版信息

J Fr Ophtalmol. 1995;18(5):331-7.

PMID:7560768

Abstract

PURPOSE

To analyze the indications or the penetrating keratoplasties which were conducted in the Bordeaux University Hospital over the 1982-1991 period and to compare these findings with those of previously published studies.

METHODS

The histopathological study of 1129 corneal buttons was analyzed according to conventional methods in the Histopathology Department Pellegrin Hospital.

RESULTS

The main indications for penetrating keratoplasty were (in decreasing order of frequency): pseudophakic or aphakic corneal oedema (28.7%), keratoconus (12.1%), regrafts (11.1%), and corneal scars (10.7%). Less frequent indications for penetrating keratoplasty included Fuchs' endothelial dystrophy (7.8%); corneal trauma (7.3%) and herpes (7.2%). Ophthalmological conditions requiring penetrating keratoplasty fall into six groups of unequal size: 1) corneal oedema (28.7%); 2) keratitis (26%); 3) dystrophies (23.2%); 4) graft failures (11.1%); 5) trauma and chemical burns (8%) and 6) miscellaneous (2.9%).

CONCLUSION

The authors emphasize the importance of studying histologically the corneal buttons after penetrating keratoplasty. Corneal oedema after cataract surgery is shown, based on the data presented, to be the main indication for penetrating keratoplasty.

摘要

目的

分析1982 - 1991年期间在波尔多大学医院进行穿透性角膜移植术的适应证，并将这些结果与先前发表的研究结果进行比较。

方法

在佩勒格林医院病理科，按照常规方法对1129个角膜植片进行组织病理学研究。

结果

穿透性角膜移植术的主要适应证（按频率递减顺序）为：人工晶状体眼或无晶状体眼角膜水肿（28.7%）、圆锥角膜（12.1%）、再次移植（11.1%）和角膜瘢痕（10.7%）。穿透性角膜移植术较不常见的适应证包括富克斯内皮营养不良（7.8%）、角膜外伤（7.3%）和疱疹（7.2%）。需要进行穿透性角膜移植术的眼科疾病分为六组，大小不等：1）角膜水肿（28.7%）；2）角膜炎（26%）；3）营养不良（23.2%）；4）移植失败（11.1%）；5）外伤和化学烧伤（8%）；6）其他（2.9%）。