Sakai F, Yoshida S, Endo S, Tomita H
Department of Otorhinolaryngology, Nihon University School of Medicine, Tokyo.
Nihon Jibiinkoka Gakkai Kaiho. 1995 Jul;98(7):1135-9. doi: 10.3950/jibiinkoka.98.1135.
We studied the therapeutic efficacy of zinc picolinate in patients with zinc-deficient and idiopathic taste disorders. Efficacy was assessed in a double-blind study. The following findings were obtained: 1. There was a significant difference between the zinc picolinate and placebo groups in the grade of improvement shown by the filter-paper disk method. 2. There was a significant difference between the zinc picolinate and placebo groups in the serum zinc concentration. 3. There was no significant difference between the two groups in the degree of total subjective recovery or the grade of improvement, as shown by in the whole mouth method. 4. We conclude that the administration of zinc picolinate is effective for patients with zinc-deficient and idiopathic taste disorders.
我们研究了吡啶甲酸锌对锌缺乏和特发性味觉障碍患者的治疗效果。在一项双盲研究中评估了疗效。获得了以下结果：1. 吡啶甲酸锌组和安慰剂组在滤纸片法显示的改善程度上存在显著差异。2. 吡啶甲酸锌组和安慰剂组在血清锌浓度上存在显著差异。3. 如全口法所示，两组在总体主观恢复程度或改善等级上没有显著差异。4. 我们得出结论，吡啶甲酸锌给药对锌缺乏和特发性味觉障碍患者有效。
