Henderson J, Culkin D, Mata J, Wilson M, Venable D
Department of Urology, Louisiana State University Medical Center, Shreveport, USA.
J Urol. 1995 Nov;154(5):1748-51.
Recipients of silicone gel filled testicular prostheses were evaluated for the possible immunological abnormalities of human adjuvant disease.
Medical record audits were performed for 48 recipients of a silicone gel filled testicular prosthesis. Seven patients consented to a detailed health profile questionnaire, physical examination and serological testing.
Retrospective chart analyses and physical examinations were unremarkable. Serological results and questionnaire responses varied. One patient with signs and symptoms suggestive of human adjuvant disease underwent prosthesis removal but adjacent tissues had no evidence of silicosis. Long-term followup was poor.
Immunological alterations were present in 71.4% of examined recipients but they may have been coincidental. Careful followup of recipients of a silicone gel filled testicular prosthesis is needed.
对接受硅胶填充睾丸假体的患者进行评估，以确定是否存在人类佐剂病的可能免疫异常情况。
对48例接受硅胶填充睾丸假体的患者进行病历审查。7例患者同意填写详细的健康状况问卷、接受体格检查和血清学检测。
回顾性病历分析和体格检查未发现异常。血清学结果和问卷回复各不相同。1例有人类佐剂病体征和症状的患者接受了假体移除，但相邻组织没有矽肺证据。长期随访情况不佳。
71.4%的受检患者存在免疫改变，但这些改变可能是巧合。需要对接受硅胶填充睾丸假体的患者进行仔细随访。
