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细粒棘球绦虫(马和羊株)与多房棘球绦虫在化学成分和碳水化合物代谢方面的差异。

Differences in the chemical composition and carbohydrate metabolism of Echinococcus granulosus (horse and sheep strains) and E. multilocularis.

作者信息

McManus D P, Smyth J D

出版信息

Parasitology. 1978 Aug;77(1):103-9. doi: 10.1017/s0031182000048769.

DOI:10.1017/s0031182000048769
PMID:756521
Abstract

Metabolic studies in vitro and studies on chemical composition indicate basic biochemical differences between the horse and sheep strains of Echinococcus granulosus and between these and the closely related species, E. multilocularis. The horse strain of E. granulosus has a similar level of DNA, but significantly more polysaccharides and lipids, with less RNA and protein than the sheep strain. E. multilocularis has significantly more lipids and DNA but less polysaccharides than the horse and sheep strains of E. granulosus, more RNA and protein than the horse strain but similar protein to and less RNA than the sheep strain. Incubations under air and under 95% N2-5% CO2 for 3 h show that only E. multilocularis takes up glucose, that all three forms consume different amounts of oxygen and endogenous glycogen and produce different concentrations of lactate, succinate, acetate, malate, pyruvate, propionate and ethanol as end products of carbohydrate metabolism.

摘要

体外代谢研究和化学成分研究表明,细粒棘球绦虫的马株和羊株之间以及它们与密切相关的多房棘球绦虫之间存在基本的生化差异。细粒棘球绦虫的马株具有相似水平的DNA,但多糖和脂质明显更多,RNA和蛋白质比羊株少。多房棘球绦虫的脂质和DNA明显多于细粒棘球绦虫的马株和羊株,但多糖少于它们,RNA和蛋白质比马株多,但蛋白质与羊株相似且RNA比羊株少。在空气和95% N₂ - 5% CO₂ 条件下孵育3小时表明,只有多房棘球绦虫摄取葡萄糖,这三种形态消耗不同量的氧气和内源性糖原,并产生不同浓度的乳酸、琥珀酸、乙酸、苹果酸、丙酮酸、丙酸和乙醇作为碳水化合物代谢的终产物。

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