Vilkman S, Keistinen T
Department of Pulmonary Medicine, Päivärinne Hospital, Jokirinne.
Respiration. 1995;62(3):151-4. doi: 10.1159/000196411.
Tracheobronchopathia osteochondroplastica (TPO) is a rare condition of unclear cause. Sporadic cases have been published from all over the world, but some geographical differences in the occurrence may exist. The condition is characterized by cartilaginous or bony outgrowths into the lumen of the tracheobronchial tree. Clinicians should include this disease in the list of differential diagnoses when confronted with symptoms like persistent and often productive cough, haemoptysis, dyspnoea and wheeze. If the condition is extensive, there may occur unexpected and acute clinical problems. We describe the case of a young man in whom we diagnosed a severe form of TPO while examining him for asthma. This patient suffered also from ozaena and the combination of these two conditions is rather common. We also retrospectively reviewed our material of 18 cases with this condition.
气管支气管骨软骨化生（TPO）是一种病因不明的罕见病症。世界各地均有散发病例报道，但在发病率上可能存在一些地域差异。该病症的特征是气管支气管树管腔内出现软骨或骨质增生。临床医生在面对持续性且常伴有咳痰的咳嗽、咯血、呼吸困难和喘息等症状时，应将这种疾病列入鉴别诊断清单。如果病情广泛，可能会出现意想不到的急性临床问题。我们描述了一名年轻男子的病例，我们在为他检查哮喘时诊断出了严重形式的TPO。该患者还患有臭鼻症，这两种病症的合并相当常见。我们还回顾性地查阅了我们手头的18例该病症患者的资料。
