Wilkinson D
Hlabisa Hospital, KwaZulu/Natal.
S Afr Med J. 1994 Dec;84(12):844-7.
Aspects of the epidemiology and clinical features of 81 consecutive patients admitted with snakebite to a rural hospital in Zululand are reviewed. Most bites occurred during the hot season, 40% in children under 10 years of age. Thirty per cent of bites occurred at night. Most bites showed features of local envenoming only, but systemic features (neurotoxicity and haemorrhage) were encountered. Snakebite caused significant morbidity and mortality. Thirty-one per cent of admissions needed surgery; almost 50% needed more than one operation. Five per cent, all children, died. The extent of local envenoming on admission proved to be a highly sensitive indicator of risk of worsening of local envenoming, and of the development of systemic signs. The analysis has allowed the development of rational guidelines on the management of snakebite in this hospital which, it is hoped, will reduce mortality rates, and has identified several areas warranting further research.
对祖鲁兰一家乡村医院连续收治的81例蛇咬伤患者的流行病学和临床特征进行了回顾。大多数咬伤发生在炎热季节,10岁以下儿童占40%。30%的咬伤发生在夜间。大多数咬伤仅表现为局部中毒特征,但也出现了全身症状(神经毒性和出血)。蛇咬伤导致了显著的发病率和死亡率。31%的入院患者需要手术;近50%的患者需要不止一次手术。5%的患者死亡,均为儿童。入院时局部中毒的程度被证明是局部中毒恶化风险和全身症状发展的高度敏感指标。该分析有助于制定该医院蛇咬伤治疗的合理指南,有望降低死亡率,并确定了几个值得进一步研究的领域。