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良性胆管狭窄:采用现代方法进行修复及疗效观察

Benign biliary strictures: repair and outcome with a contemporary approach.

作者信息

McDonald M L, Farnell M B, Nagorney D M, Ilstrup D M, Kutch J M

机构信息

Department of Surgery, Mayo Clinic, Rochester, MN 55905, USA.

出版信息

Surgery. 1995 Oct;118(4):582-90; discussion 590-1. doi: 10.1016/s0039-6060(05)80022-4.

Abstract

BACKGROUND

The Hepp-Couinaud technique is an innovative approach for repair of proximal biliary strictures. We have used this method selectively for bile duct reconstruction since 1982. Our aim was to analyze our experience with the surgical repair of benign biliary strictures in the decade since the Hepp-Couinaud technique has become an integral component of our surgical management strategy.

METHODS

Seventy-two patients undergoing surgical repair of benign biliary stricture between 1983 and 1992 were reviewed retrospectively. A grading system on clinical symptoms, results of liver function studies, and need for reintervention was used to assess outcome.

RESULTS

For the 27 patients with noniatrogenic strictures, followed up a mean of 3.9 years, excellent or good results (grade A or B) were obtained in 88.9%. For the 45 patients with iatrogenic strictures, followed up a mean of 4.6 years, 86.7% were categorized as grade A or B. The cumulative probability of anastomotic failure was significantly less for the 21 patients in whom the Hepp-Couinaud method was used when compared with the 24 patients in whom it was not (p = 0.032). Outcome was not influenced by age, time delay from injury to reconstruction, preoperative stenting, the number of previous repairs, or the duration of postoperative stenting.

CONCLUSIONS

Surgical reconstruction affords excellent or good results for the vast majority of patients with benign biliary strictures. For proximal iatrogenic strictures superior anastomotic durability is achieved with the Hepp-Couinaud technique.

摘要

背景

赫普-库伊纳德技术是一种用于修复近端胆管狭窄的创新方法。自1982年以来,我们选择性地使用这种方法进行胆管重建。我们的目的是分析自赫普-库伊纳德技术成为我们手术管理策略的一个组成部分后的十年里,我们在良性胆管狭窄手术修复方面的经验。

方法

回顾性分析了1983年至1992年间接受良性胆管狭窄手术修复的72例患者。采用一个基于临床症状、肝功能检查结果和再次干预需求的分级系统来评估预后。

结果

27例非医源性狭窄患者,平均随访3.9年,88.9%获得了优良结果(A级或B级)。45例医源性狭窄患者,平均随访4.6年,86.7%被归类为A级或B级。与未使用赫普-库伊纳德方法的24例患者相比,使用该方法的21例患者吻合口失败的累积概率显著更低(p = 0.032)。预后不受年龄、受伤至重建的时间延迟、术前支架置入、既往修复次数或术后支架置入持续时间的影响。

结论

手术重建为绝大多数良性胆管狭窄患者带来优良结果。对于近端医源性狭窄,赫普-库伊纳德技术可实现更好的吻合口耐久性。

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