Zifko U, Auinger M, Albrecht G, Kästenbauer T, Lahrmann H, Grisold W, Wanke T
Neurological Department, Kaiser Franz Josef Spital and L. Boltzmann Institute of Neurobiology, Krankenhaus Baumgartner Höhe, Vienna, Austria.
Thorax. 1995 Jul;50(7):793-4. doi: 10.1136/thx.50.7.793.
Peripheral neuropathy and alterations in diaphragmatic muscle function are frequently caused by uraemia. Phrenic nerve function in patients with end stage renal failure, however, has not been examined to date.
An electrophysiological study of the phrenic nerve was performed to determine its possible involvement in 32 nondiabetic patients with end stage renal disease undergoing chronic haemodialysis.
Seventeen patients had electrophysiological signs of peripheral neuropathy in at least one of the investigated nerves and 14 of the 17 showed pathological phrenic nerve latencies. Delayed phrenic nerve latencies correlated clearly with pathological peroneal nerve conduction velocities.
Phrenic neuropathy is a frequent complication of uraemia.
周围神经病变和膈肌功能改变常由尿毒症引起。然而，迄今为止尚未对终末期肾衰竭患者的膈神经功能进行过检查。
对32例接受慢性血液透析的非糖尿病终末期肾病患者进行膈神经电生理研究，以确定膈神经是否受累。
17例患者至少在一条被检查神经中存在周围神经病变的电生理迹象，其中14例膈神经潜伏期异常。膈神经潜伏期延长与腓总神经传导速度异常明显相关。
膈神经病变是尿毒症常见的并发症。
