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腹腔镜胆囊切除术后49例胆管损伤修复的结果

Outcome of 49 repairs of bile duct injuries after laparoscopic cholecystectomy.

作者信息

Schol F P, Go P M, Gouma D J

机构信息

Department of Surgery, University Hospital Maastricht, The Netherlands.

出版信息

World J Surg. 1995 Sep-Oct;19(5):753-6; discussion 756-7. doi: 10.1007/BF00295923.

DOI:10.1007/BF00295923
PMID:7571676
Abstract

Treatment of bile duct injuries after laparoscopic cholecystectomy is still under discussion. The aim of this study was to evaluate the results of end-to-end or biliodigestive anastomosis for various types of bile duct injury. Patient charts of 49 (0.81%) classified bile duct injuries from a national survey of 6076 laparoscopic cholecystectomies in The Netherlands were analyzed. The median follow-up after repair was 183 days (range 14-570 days). Statistical analysis showed that an end-to-end anastomosis was preferred by the surgeons for less severe bile duct injuries and a biliodigestive repair for more severe injuries. Three patients died owing to a delayed detected bile duct injury. Twelve bile duct strictures occurred after repair, leading to a stricture rate of 25%. The time elapsed between repair and occurrence of a stricture was 134 days (range 13-270 days). The type of repair or the severity of the bile duct injury did not determine the outcome of the repair. Histologically proved cholecystitis predisposed a stricture at the repair site. It was concluded that treatment of bile duct injuries is associated with a high stricture rate at the repair site of the anastomosis. End-to-end anastomosis is mostly successful for the less severe injury detected during laparoscopic cholecystectomy. For all other cases this repair can at least be considered a temporary internal drainage procedure. The biliodigestive anastomosis can best be considered a delayed repair after a drainage procedure has resolved the local inflammatory status.

摘要

腹腔镜胆囊切除术后胆管损伤的治疗仍在讨论之中。本研究的目的是评估各种类型胆管损伤的端端吻合或胆肠吻合的结果。分析了荷兰全国6076例腹腔镜胆囊切除术调查中49例(0.81%)分类胆管损伤的患者病历。修复后的中位随访时间为183天(范围14 - 570天)。统计分析表明,对于不太严重的胆管损伤,外科医生更倾向于端端吻合,而对于更严重的损伤则采用胆肠修复。3例患者因胆管损伤发现延迟死亡。修复后发生12例胆管狭窄,狭窄率为25%。修复与狭窄发生之间的时间为134天(范围13 - 270天)。修复类型或胆管损伤的严重程度并未决定修复的结果。组织学证实的胆囊炎易导致修复部位狭窄。得出的结论是,胆管损伤的治疗与吻合修复部位的高狭窄率相关。端端吻合对于腹腔镜胆囊切除术中发现的不太严重的损伤大多是成功的。对于所有其他病例,这种修复至少可被视为一种临时内引流手术。胆肠吻合最好被视为在引流手术解决局部炎症状态后的延迟修复。

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J Gastrointest Surg. 2019 Feb;23(2):408-416. doi: 10.1007/s11605-018-4027-z. Epub 2018 Nov 6.
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Management of Bile Duct Injury at Various Stages of Presentation: Experience from a Tertiary Care Centre.不同就诊阶段胆管损伤的管理:来自三级医疗中心的经验
Indian J Surg. 2015 Apr;77(2):92-8. doi: 10.1007/s12262-012-0722-2. Epub 2012 Sep 25.
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Management of post-cholecystectomy benign bile duct strictures: review.

本文引用的文献

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Diagnosis and management of biliary complications of laparoscopic cholecystectomy.腹腔镜胆囊切除术胆道并发症的诊断与处理
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Management of major biliary complications after laparoscopic cholecystectomy.腹腔镜胆囊切除术后主要胆道并发症的处理
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Bile duct complications after laparoscopic cholecystectomy.腹腔镜胆囊切除术后的胆管并发症
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Ann Surg. 2001 Dec;234(6):750-7. doi: 10.1097/00000658-200112000-00006.
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J Gastrointest Surg. 1997 Mar-Apr;1(2):138-45; discussion 145. doi: 10.1016/s1091-255x(97)80101-1.
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Am J Surg. 1993 Jan;165(1):9-14. doi: 10.1016/s0002-9610(05)80397-6.
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Gut. 1993 Sep;34(9):1250-4. doi: 10.1136/gut.34.9.1250.
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