Min Y G, Chung J W, Shin J S, Chi J G
Department of Otorhinolaryngology, College of Medicine, Seoul National University, Korea.
Acta Otolaryngol. 1995 Jul;115(4):543-7. doi: 10.3109/00016489509139364.
The antrochonanal polyp (ACP) is defined as a maxillary sinus polyp that originates in the maxillary sinus, passes through the sinus ostia, and extends into the choana. The aim of this study was to compare the histologic findings of 40 cases of ACP with those of allergic and non-allergic nasal polyps, and so possibly to elucidate the pathogenesis of ACP. No allergy could be verified in any of the ACP patients. Inflammatory cell infiltration was significantly more severe in the ACP group than in the allergic polyp group. Eosinophilic infiltration was significantly less severe in the ACP group than in the allergic polyp group. Edema was not significantly different between the ACP, allergic, and non-allergic groups. In the ACP group, the presence of submucous glands was significantly less pronounced than in the ordinary nasal polyp groups. The fibrous type was present significantly more often than the infiltrative or granulating type in the ACP group. The histologic findings and clinical features of the ACP indicate that it has little causal relationship with nasal allergy but is all the more intimately associated with inflammatory processes. The paucity of submucous glands suggests that the ACP results from edematous hypertrophy of the respiratory epithelium rather than from distension of the glandular structures.
上颌窦后鼻孔息肉（ACP）被定义为起源于上颌窦、通过窦口并延伸至后鼻孔的上颌窦息肉。本研究的目的是比较40例ACP与变应性和非变应性鼻息肉的组织学表现，从而可能阐明ACP的发病机制。在任何一例ACP患者中均未证实存在变应性。ACP组的炎性细胞浸润明显比变应性息肉组严重。ACP组的嗜酸性粒细胞浸润明显比变应性息肉组轻。ACP组、变应性组和非变应性组之间的水肿无显著差异。在ACP组，黏膜下腺的存在明显不如普通鼻息肉组明显。在ACP组，纤维型的出现明显比浸润型或肉芽型更常见。ACP的组织学表现和临床特征表明，它与鼻变应性几乎没有因果关系，但与炎症过程关系更为密切。黏膜下腺的稀少提示ACP是由呼吸上皮的水肿性肥大而非腺结构的扩张所致。
