Helbing W A, Rebergen S A, Maliepaard C, Hansen B, Ottenkamp J, Reiber J H, de Roos A
Department of Pediatrics (subdivision of Pediatric Cardiology), University Hospital, Leiden, The Netherlands.
Am Heart J. 1995 Oct;130(4):828-37. doi: 10.1016/0002-8703(95)90084-5.
In clinical treatment of children with congenital heart disease (CHD) assessment of right ventricular (RV) function is important. Available imaging techniques have been of limited value because of technical factors and the complex geometry of the right ventricle. To validate magnetic resonance (MR) imaging measurements of RV function in children, gradient echo MR imaging of both ventricles and MR flow mapping of great vessel and tricuspid flow was performed in 20 children with CHD affecting the right ventricle and in 22 healthy children ranging in age from 5 to 16 years. Close correlation between RV versus LV stroke volumes (r = 0.96) and RV stroke volume versus great artery (r = 0.97) or tricuspid flow (r = 0.97) was observed with small interobserver and intraobserver variability. Results of healthy children were end-diastolic volume: 70 +/- 9 ml/m2, end-systolic volume: 21 +/- 5 ml/m2, and ejection fraction: 70% +/- 4%. In the patient groups clinically important differences were noted. We conclude that MR imaging provides accurate noninvasive measurements of RV function in healthy children and patients with (operated) CHD.
在先天性心脏病（CHD）患儿的临床治疗中，右心室（RV）功能评估至关重要。由于技术因素以及右心室复杂的几何结构，现有的成像技术价值有限。为验证儿童右心室功能的磁共振（MR）成像测量，对20例影响右心室的先天性心脏病患儿以及22例年龄在5至16岁的健康儿童进行了双心室梯度回波MR成像以及大血管和三尖瓣血流的MR血流图检查。观察到右心室与左心室每搏量之间（r = 0.96）以及右心室每搏量与大动脉（r = 0.97）或三尖瓣血流（r = 0.97）之间具有密切相关性，观察者间和观察者内变异性较小。健康儿童的结果为：舒张末期容积：70±9 ml/m²，收缩末期容积：21±5 ml/m²，射血分数：70%±4%。在患者组中注意到了具有临床意义的差异。我们得出结论，MR成像能够对健康儿童以及患有（已手术）先天性心脏病的患者的右心室功能进行准确的无创测量。
