Pattynama P M, Lamb H J, Van der Velde E A, Van der Geest R J, Van der Wall E E, De Roos A
Department of Radiology, University Hospital Leiden, The Netherlands.
Magn Reson Imaging. 1995;13(1):53-63. doi: 10.1016/0730-725x(94)00076-f.
Magnetic resonance (MR) imaging has been shown to provide accurate measurements of right ventricular (RV) volumes and myocardial mass. The purpose of this study was to evaluate the reproducibility of MR imaging, which in clinical practice may be as important as its absolute accuracy. The reproducibility of MR imaging measurements of the right ventricle was assessed by analyzing 40 serial functional MR imaging examinations of the right ventricle with variance component analysis. Standard deviations and 95% ranges for change were: for RV myocardial mass, 5.9 and 16 g; and for RV ejection fraction, 6.0% and 16%, respectively. Reproducibility was similar for cine and spin-echo MR imaging. The intraobserver and interobserver errors were especially large, indicating that observer subjectivity is the limiting factor in the interpretation of the MR images. This study suggests that the reproducibility of RV measurements is adequate to detect RV hypertrophy and a low ejection fraction in the individual patient. For accurate follow-up examinations, whereby smaller changes are to be detected, the reproducibility of MR imaging measurements may not be sufficient. More effort is needed to improve the reproducibility of MR imaging measurements.
磁共振（MR）成像已被证明能准确测量右心室（RV）容积和心肌质量。本研究的目的是评估MR成像的可重复性，在临床实践中，其可重复性可能与其绝对准确性同样重要。通过对40次右心室连续功能性MR成像检查进行方差成分分析，评估右心室MR成像测量的可重复性。右心室心肌质量变化的标准差和95%范围分别为：5.9 g和16 g；右心室射血分数变化的标准差和95%范围分别为：6.0%和16%。电影成像和自旋回波MR成像的可重复性相似。观察者内和观察者间误差特别大，表明观察者的主观性是MR图像解读中的限制因素。本研究表明，右心室测量的可重复性足以检测个体患者的右心室肥厚和低射血分数。对于需要检测较小变化的准确随访检查，MR成像测量的可重复性可能不足。需要付出更多努力来提高MR成像测量的可重复性。
