Nomoto Y, Kawaguchi Y, Ohira S, Yuri T, Kubo H, Kubota M, Nihei H, Nakao T, Hara S, Nakamoto M
Department of Internal Medicine, School of Medicine, Tokai University Isehara City, Japan.
Am J Nephrol. 1995;15(4):295-9. doi: 10.1159/000168852.
Patients undergoing continuous ambulatory peritoneal dialysis (CAPD) who developed carpal tunnel syndrome (CTS) were retrospectively studied in 143 centers in Japan. Among the total 5,050 patients undergoing CAPD between 1980 and 1993 only 7 patients (0.14%) given CAPD developed CTS. Five of these 7 patients treated solely with CAPD developed CTS 12-108 months after starting CAPD. The remaining 2 patients who were initially treated with HD for 7-9 years and then switched to CAPD developed this complication 9 years after starting CAPD. All 7 patients were women, ranging in age from 32 to 70 (average 52) years. We detected the presence of amyloid deposits in 2 of 5 specimens and beta 2-microglobulin in 2 of 4 specimens from these patients. It was concluded that CAPD minimizes the emergence of CTS although constant surveillance is necessary to detect CTS in patients during CAPD.
日本143个中心对接受持续性非卧床腹膜透析（CAPD）并发腕管综合征（CTS）的患者进行了回顾性研究。在1980年至1993年间接受CAPD治疗的5050例患者中，仅有7例（0.14%）发生了CTS。这7例患者中，5例单纯接受CAPD治疗，在开始CAPD治疗12 - 108个月后发生CTS。其余2例最初接受血液透析（HD）治疗7 - 9年，之后转为CAPD治疗，在开始CAPD治疗9年后发生了这种并发症。所有7例患者均为女性，年龄在32岁至70岁之间（平均52岁）。我们在这些患者的5份标本中的2份检测到淀粉样沉积物，在4份标本中的2份检测到β2-微球蛋白。得出的结论是，尽管在CAPD治疗期间对患者进行CTS监测很有必要，但CAPD可使CTS的发生率降至最低。
