Chung Y J, Choi K C, Ha J H, Kim K Y, Lee S C, Kim S W, Kim N H, Kang Y J, Moon E S, Lee M C
Department of Internal Medicine, Chonnam University Medical School, Kwangju, Korea.
Korean J Intern Med. 1997 Jan;12(1):75-9. doi: 10.3904/kjim.1997.12.1.75.
Carpal tunnel syndrome (CTS) is characterized by burning pain, numbness and tingling sensation in the thumb, index and middle fingers and the lateral half of the palm and progressive atrophy of the thenar muscles by compression of the median nerve within the carpal tunnel due to a variety of etiologic factors. Surgical intervention usually successfully relieves symptoms of CTS. Recently CTS has been regarded as one of the major clinical manifestations of dialysis-related amyloidosis due to beta 2-microglobulin deposition and recognized with increasing frequency in patients undergoing long-term hemodialysis. We report a case of carpal tunnel syndrome due to dialysis-related amyloidosis in patients undergoing long-term hemodialysis, confirmed by electromyography and biopsy in transverse carpal ligament and median nerve.
腕管综合征（CTS）的特征是拇指、示指和中指以及手掌外侧半出现灼痛、麻木和刺痛感，由于多种病因导致腕管内正中神经受压，进而出现鱼际肌进行性萎缩。手术干预通常能成功缓解CTS的症状。近来，CTS被认为是由β2微球蛋白沉积所致的透析相关淀粉样变的主要临床表现之一，并且在长期血液透析患者中越来越频繁地被发现。我们报告1例长期血液透析患者因透析相关淀粉样变导致的腕管综合征，经肌电图检查以及腕横韧带和正中神经活检得以确诊。
