Kameyama M, Higashiyama M, Nakamori S, Kodama K, Imaoka S, Doi O, Iwanaga T, Naruse Y, Horai T
Dept. of Surgery, Center for Adult Diseases, Osaka.
Gan To Kagaku Ryoho. 1995 Sep;22(11):1616-8.
Seventeen patients with lung metastases from colorectal cancer underwent intraoperative pleural lavage cytology immediately after thoracotomy from August 1988 to December 1994. Patients with pleural effusion and/or dissemination were excluded. The median followup period was 34 months (range 3-52 months). Of the 17 patients, 13 were cytologically negative (76%, group A) and 4 were positive (24% group B). Recurrence rate in the pleural cavity was 25% (1/4) in group B and 0% (0/13) in group A. The three-year survival rate was 0% in group B and 78% in group A, respectively. These results indicate that intraoperative pleural lavage cytology is useful in the assessment of prognosis, and locoregional therapy should be considered for cytology positive group.
1988年8月至1994年12月期间，17例结直肠癌肺转移患者在开胸术后立即接受了术中胸腔灌洗细胞学检查。有胸腔积液和/或播散的患者被排除在外。中位随访期为34个月（范围3 - 52个月）。17例患者中，13例细胞学检查为阴性（76%，A组），4例为阳性（24%，B组）。B组胸腔复发率为25%（1/4），A组为0%（0/13）。B组三年生存率为0%，A组为78%。这些结果表明，术中胸腔灌洗细胞学检查有助于评估预后，细胞学阳性组应考虑进行局部区域治疗。
