Kurwa H A, Finlay A Y
Department of Dermatology, University of Wales College of Medicine, Cardiff, U.K.
Br J Dermatol. 1995 Oct;133(4):575-8. doi: 10.1111/j.1365-2133.1995.tb02708.x.
The aim of this study was to measure the effect of in-patient management on the quality of life of adult dermatology patients, and to identify the diagnostic categories which show the greatest improvement. Over a 6-month period, all 230 patients admitted to the dermatology ward of the University Hospital of Wales were invited to complete a Dermatology Life Quality Index (DLQI) questionnaire on admission, and again 4 weeks after discharge. Two hundred and seventeen (93%) of these patients entered the study, and 181 (83.4%) returned both questionnaires. The mean DLQI on admission was 13.2 (standard deviation [SD] 7.6; n = 181), and 4 weeks after discharge it was 7.7 (SD 6.8; P < 0.001). Seventy-three per cent of the 181 patients showed improvement, 5.5% remained unchanged, and 21.5% worsened. Patients with psoriasis improved from 13.7 (SD 6.5) to 6.7 (SD 5.6; n = 63; P < 0.001), and those with eczema improved from 16.2 (SD 6.3) to 9.6 (SD 7.6; n = 56; P < 0.001). Patients with pruritus showed little improvement, as did those admitted for liver biopsy. Patients with psoriasis and severe eczema showed, overall, a significant decrease in impairment of life quality following in-patient treatment. Severe eczema has a greater adverse impact on the quality of life than severe psoriasis. The parameters for which most improvement was seen were those which were of most concern to the patients, i.e. their symptoms (score after discharge = 1.2; DS 0.9; P < 0.001) and their embarrassment (0.9; SD 1.0; P < 0.001).
本研究的目的是衡量住院治疗对成年皮肤科患者生活质量的影响,并确定改善最为显著的诊断类别。在6个月的时间里,威尔士大学医院皮肤科病房收治的所有230名患者被邀请在入院时以及出院4周后再次填写一份皮肤病生活质量指数(DLQI)问卷。其中217名(93%)患者进入研究,181名(83.4%)患者返还了两份问卷。入院时DLQI的平均值为13.2(标准差[SD]7.6;n = 181),出院4周后为7.7(SD 6.8;P < 0.001)。181名患者中73%有改善,5.5%无变化,21.5%病情恶化。银屑病患者从13.7(SD 6.5)改善至6.7(SD 5.6;n = 63;P < 0.001),湿疹患者从16.2(SD 6.3)改善至9.6(SD 7.6;n = 56;P < 0.001)。瘙痒症患者改善甚微,接受肝脏活检的患者也是如此。总体而言,银屑病和重度湿疹患者在接受住院治疗后生活质量受损情况显著下降。重度湿疹对生活质量的不利影响比重度银屑病更大。改善最为明显的参数是患者最为关注的参数,即他们的症状(出院后得分 = 1.2;DS 0.9;P < 0.001)和他们的尴尬感(0.9;SD 1.0;P < 0.001)。