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Phenotype differences of STRs in 7 human populations.

作者信息

Meyer E, Wiegand P, Brinkmann B

机构信息

Institute of Legal Medicine, Westfälische Wilhelms-Universität, Münster, Germany.

出版信息

Int J Legal Med. 1995;107(6):314-22. doi: 10.1007/BF01246881.

DOI:10.1007/BF01246881
PMID:7577696
Abstract

A maximum of 6 STR systems (TH01, VWA, ACTBP2, FES, F13B, D21S11) was investigated in 7 human populations (Germans, Turks, Moroccans, Japanese, Chinese, Papuans, Ovambos). In each population no deviations from Hardy-Weinberg equilibrium were observed. Out of each population the phenotypes of 50 individuals (comprising 3 to 6 STRs) were randomly selected. Based on the phenotype frequencies interpopulation comparisons were carried out using the frequencies of each other population. Within major ethnic groups only minor differences in phenotype frequencies were found. Between major ethnic groups differences of up to several orders of magnitude could be observed. The most discriminative STRs for interpopulation comparisons were TH01, FES and F13B.

摘要

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本文引用的文献

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Eur J Hum Genet. 1996;4(3):175-82. doi: 10.1159/000472192.
2
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Int J Legal Med. 1993;105(6):315-20. doi: 10.1007/BF01222114.
3
The forensic significance of various reference population databases for estimating the rarity of variable number of tandem repeat (VNTR) loci profiles.
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4
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5
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Int J Legal Med. 1993;106(2):81-3. doi: 10.1007/BF01225045.
6
Identification of repeat sequence heterogeneity at the polymorphic short tandem repeat locus HUMTH01[AATG]n and reassignment of alleles in population analysis by using a locus-specific allelic ladder.利用位点特异性等位基因分型标准物鉴定多态性短串联重复序列位点HUMTH01[AATG]n处的重复序列异质性并在群体分析中重新指定等位基因
Am J Hum Genet. 1993 Oct;53(4):953-8.
7
A microsatellite polymorphism in the von Willebrand factor gene: comparison of allele frequencies in different population samples and evaluation for forensic medicine.
Forensic Sci Int. 1994 Sep 16;68(2):91-102. doi: 10.1016/0379-0738(94)90307-7.
8
PCR typing of DNA fragments of the short tandem repeat (STR) system HUMTH01 in Danes and Greenland Eskimos.丹麦人和格陵兰爱斯基摩人中短串联重复序列(STR)系统HUMTH01的DNA片段的聚合酶链反应(PCR)分型
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9
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