Bramson J L, Graham F L, Gauldie J
McMaster University, Hamilton, Canada.
Curr Opin Biotechnol. 1995 Oct;6(5):590-5. doi: 10.1016/0958-1669(95)80097-2.
Adenoviral vectors have proven to be excellent vehicles for gene delivery in vivo to a wide range of cell types. These vectors have been used to transfer genes such as CFTR to correct the defect in cystic fibrosis and, more recently, to supply serum blood factors and genetically modify tumors to enhance therapy.
腺病毒载体已被证明是在体内将基因传递到多种细胞类型的优良载体。这些载体已被用于转移如CFTR等基因以纠正囊性纤维化中的缺陷，并且最近还用于提供血清血液因子以及对肿瘤进行基因改造以增强治疗效果。
