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全胃切除术后继发性夸希奥科病的成功手术治疗:病例报告

Successful surgical treatment of secondary Kwashiorkor after total gastrectomy: report of a case.

作者信息

Kadowaki A, Tajima T, Kogure H, Tajima Y

机构信息

Second Department of Surgery, Dokkyo University School of Medicine, Tochigi, Japan.

出版信息

Surg Today. 1995;25(6):548-51. doi: 10.1007/BF00311313.

Abstract

We report herein the case of a 56-year-old woman who developed secondary Kwashiorkor 9 years after undergoing a total gastrectomy for early gastric cancer. Until she began developing the symptoms of Kwashiorkor, including general fatigue, edema of the face and extremities, anemia, alopecia, and weight loss, she had been leading a normal life post-gastrectomy. Her symptoms were alleviated by total parenteral nutrition (TPN) therapy, but reappeared soon after TPN therapy was discontinued. Therefore, she required several subsequent courses of TPN. In an attempt to permanently resolve the ongoing Kwashiorkor symptoms, reconstructive surgery involving transposition of the jejunum from the previous Graham method to the interposition method was performed 10 years after the initial gastrectomy. After the second operation, her malnutrition was completely alleviated, and she has been in good health for the 8 years since. To our knowledge, there has been no other report of the symptoms of secondary Kwashiorkor after total gastrectomy being alleviated by altering the procedure of reconstruction of the intestinal tract. Thus, we recommend surgical treatment to alter the digestive continuity to a more physiological pathway for selected patients with secondary Kwashiorkor syndrome.

摘要

我们在此报告一例56岁女性患者,她在因早期胃癌接受全胃切除术后9年出现继发性夸希奥科病。在开始出现夸希奥科病症状(包括全身乏力、面部和四肢水肿、贫血、脱发和体重减轻)之前,她在全胃切除术后一直过着正常生活。她的症状通过全胃肠外营养(TPN)治疗得到缓解,但在TPN治疗停止后不久又再次出现。因此,她需要后续多次进行TPN治疗。为了永久解决持续存在的夸希奥科病症状,在初次全胃切除术后10年进行了重建手术,将空肠从之前的格雷厄姆法改为间置法。第二次手术后,她的营养不良完全得到缓解,此后8年一直健康状况良好。据我们所知,尚无其他关于通过改变肠道重建手术方法缓解全胃切除术后继发性夸希奥科病症状的报告。因此,我们建议对选定的继发性夸希奥科病综合征患者进行手术治疗,将消化连续性改变为更符合生理的途径。

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