Fulton J E
Institute for Skin Research, Newport Beach, California 92660, USA.
Dermatol Surg. 1995 Nov;21(11):947-51. doi: 10.1111/j.1524-4725.1995.tb00531.x.
Hypertrophic scars and keloids remain a problem for surgeons. Topical and intralesional corticosteroids, positive pressure dressings, cryotherapy, and laser therapy are helpful but not uniformly successful.
To document the effectiveness of silicone gel sheeting in the prevention and/or reduction of evolving hypertrophic scars and keloids.
Silicone gel sheeting was placed over evolving scars in 20 cases. The dressing was worn for at least 12 hours a day. Biopsies were examined for the presence of silica in the tissue.
Lesions improved during the treatment period in 85% of the cases. The mechanisms of action are unknown. Positive pressure was not necessary. No silica from the dressing was found at the wound site.
Daily treatments with silicone gel sheeting should begin as soon as an itchy red streak develops in a maturing wound. The dressing is effective in reducing the bulk of these lesions.
增生性瘢痕和瘢痕疙瘩对外科医生来说仍然是个难题。局部和病灶内注射皮质类固醇、正压敷料、冷冻疗法和激光疗法虽有帮助,但并非全都能成功。
记录硅胶片在预防和/或减轻正在形成的增生性瘢痕和瘢痕疙瘩方面的有效性。
在20例患者正在形成的瘢痕上放置硅胶片。敷料每天至少佩戴12小时。对活检组织进行检查,以确定组织中是否存在硅。
85%的病例在治疗期间病变有所改善。作用机制尚不清楚。正压并非必需。在伤口部位未发现来自敷料的硅。
一旦成熟伤口出现瘙痒的红色条纹,就应尽快开始每日使用硅胶片治疗。该敷料在减轻这些病变的体积方面有效。