Dudek I M, Kedziora J, Zagórski T, Chmielewski H, Lisiewicz J, Mazurek M
Department of Medical Physiology, Military Medical Academy, Lodz, Poland.
Int J Occup Med Environ Health. 1995;8(2):109-14.
The influence of ethanol consumption on acetylcholinesterase (AchE) and Na+, K+ -ATP-ase activities was examined in 14 healthy volunteers after 30 minutes of ethanol treatment at a dose 0.6 g/kg of body weight. It was observed that the activity of both enzymes decreased. The activity of AchE was significantly lower, and that of Na+, K+ -ATP-ase tended to be lower, but the difference was not significant. In vitro experiments showed that ethanol inhibited the AchE and N+, K+ -ATP-ase activities immediately and in proportion to the concentration of ethanol used.
在14名健康志愿者中，以0.6克/千克体重的剂量进行30分钟乙醇处理后，研究了乙醇摄入对乙酰胆碱酯酶（AchE）和钠钾ATP酶活性的影响。观察到两种酶的活性均降低。AchE的活性显著降低，钠钾ATP酶的活性有降低趋势，但差异不显著。体外实验表明，乙醇可立即抑制AchE和钠钾ATP酶的活性，且与所用乙醇的浓度成正比。
