兔淋巴细胞上的T细胞和B细胞表面标志物。
T- and B-cell surface markers on rabbit lymphocytes.
作者信息
Sabolović N, Sabolović D, Guilmin A M
出版信息
Immunology. 1977 Apr;32(4):581-90.
Abstract
Rabbit thymus, appendix, blood and lymph nodes were characterized using immunological tests: rosette-forming ability with homologous or heterologous red blood cells, surface immunoglobulins, analytical cell-electrophoresis, cell refringency and in vitro mitogen responsiveness. The experiments were conducted on normal rabbits and cyclophosphamide-treated rabbits. Moreover, we tried to separate slow and high mobility cells by free-flow electrophoresis into fractions. These experiments suggest that rabbit lymphocyte behaviour is exceptional among mammals in that the majority of their lymphocytes appeared as B cells and that, in comparison with mouse and man, the proportions of these cells are inversed.
摘要
通过免疫测试对兔胸腺、阑尾、血液和淋巴结进行了表征：与同源或异源红细胞形成花环的能力、表面免疫球蛋白、分析性细胞电泳、细胞折射性和体外有丝分裂原反应性。实验在正常兔和环磷酰胺处理的兔身上进行。此外，我们试图通过自由流动电泳将慢速和高迁移率细胞分离成不同组分。这些实验表明，兔淋巴细胞的行为在哺乳动物中是异常的，因为它们的大多数淋巴细胞表现为B细胞，并且与小鼠和人类相比，这些细胞的比例是相反的。
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Selective depletion of lymphoid tissue by cyclophosphamide.用环磷酰胺选择性地消耗淋巴组织。
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