Mengshoel A M, Vøllestad N K, Førre O
Oslo Sanitetsforening Rheumatism Hospital, Norway.
Clin Exp Rheumatol. 1995 Jul-Aug;13(4):477-82.
To examine whether general feelings of fatigue, exercise-induced pain in the extremities, and exertion were different in female patients with fibromyalgia syndrome (FS) compared with sedentary healthy women.
Thirty-seven FS patients and 20 healthy subjects were studied. Cardiovascular fitness was assessed by Aastrand's indirect, submaximal method. The period of repetitive dynamic muscle contractions and sustained static muscle contraction were measured. General feelings of fatigue before exercise and exercise-induced extremity pain were assessed by visual analogue scales. Exercise-induced exertion was recorded by Borg's Rating Scale of Perceived Exertion.
No significant group difference in cardiovascular fitness was found (p = 0.8). In the FS patients general fatigue was (median 95% confidence interval) 69 (59 - 75) versus 32 (22 - 47) for the healthy controls (p < 0.0001). At the moment of interrupting the bicycle test, the perceived exertion score was 17 (16 - 18) among patients versus 13 (13 - 15) among controls (p < 0.0001). Compared with the controls, high exercise-induced extremity pain was found after sustained static and repetitive dynamic muscle contractions in the FS patients (p < 0.004), and 24 hours later the patients' pain intensities had not returned to pre-exercise values (p < 0.01).
High general fatigue, exercise-induced extremity pain, exertion and 24 hours post-exercise extremity pain in FS patients compared with healthy controls could not be explained by any group difference in cardiovascular fitness.
研究与久坐不动的健康女性相比，纤维肌痛综合征（FS）女性患者的总体疲劳感、运动引起的四肢疼痛和劳累程度是否存在差异。
对37例FS患者和20名健康受试者进行了研究。采用阿斯特兰德间接次最大量运动试验法评估心血管适能。测量重复性动态肌肉收缩和持续性静态肌肉收缩的时长。通过视觉模拟量表评估运动前的总体疲劳感和运动引起的肢体疼痛。采用伯格自觉劳累分级量表记录运动引起的劳累程度。
未发现两组在心血管适能方面存在显著差异（p = 0.8）。FS患者的总体疲劳感（中位数95%置信区间）为69（59 - 75），而健康对照组为32（22 - 47）（p < 0.0001）。中断自行车测试时，患者的自觉劳累评分为17（16 - 18），而对照组为13（13 - 15）（p < 0.0001）。与对照组相比，FS患者在持续性静态和重复性动态肌肉收缩后出现了较高的运动引起的肢体疼痛（p < 0.004），并且24小时后患者的疼痛强度未恢复到运动前水平（p < 0.01）。
与健康对照组相比，FS患者的总体疲劳感高、运动引起的肢体疼痛、劳累以及运动后24小时的肢体疼痛，无法用两组在心血管适能方面的差异来解释。
