Littler W A
Am Heart J. 1979 Jan;97(1):35-7. doi: 10.1016/0002-8703(79)90111-x.
Twenty-seven healthy people with a wide range of casual blood pressure readings (120/70 to 230/120 mm. Hg) had their blood pressure recorded continuously over a 24-hour period. Arterial pressure fell during sleep and only rose appreciably after the patients had awakened and a further rise was associated with physical activity, once they were out of bed. This pattern was observed in 18 untreated patients and in nine currently receiving hypotensive treatment. This study suggests that arterial pressure is not specifically related to time and is chiefly governed by physical activity and sleep.
27名血压值范围较广（收缩压120/70至230/120毫米汞柱）的健康人在24小时内持续记录血压。睡眠期间动脉压下降，患者醒来后才会明显上升，一旦起床，进一步的血压上升与身体活动有关。在18名未经治疗的患者和9名正在接受降压治疗的患者中均观察到这种模式。这项研究表明，动脉压与时间并无特定关联，主要受身体活动和睡眠的支配。
