Roses D F, Harris M N, Stern J S, Gumport S L
Ann Surg. 1979 Jan;189(1):112-5. doi: 10.1097/00000658-197901000-00021.
A series of 21 patients treated surgically for primary melanoma of the skin of the breast has been studied. Melanomas in this location accounted for 1.8% of a total of 1,140 patients with primary clinical Stage I and Stage II melanomas treated during a 28 year period. Wide excision with axillary lymph node dissection in selected instances has resulted in no mortality and no local recurrence to date. This approach allowed the preservation of a major portion of the breast in eight female patients. It is emphasized that melanoma is a cutaneous lesion and considerations applying to lymphatic dissemination of parenchymal disease of the breast need not apply.
对21例接受手术治疗的乳腺原发性皮肤黑色素瘤患者进行了研究。该部位的黑色素瘤在28年期间接受治疗的1140例原发性临床I期和II期黑色素瘤患者中占1.8%。在部分病例中进行广泛切除并辅以腋窝淋巴结清扫,至今未出现死亡病例和局部复发。这种方法使得8例女性患者的大部分乳房得以保留。需要强调的是,黑色素瘤是一种皮肤病变,适用于乳腺实质疾病淋巴扩散的考虑因素并不适用。