Gray G E, Pike M C, Henderson B E
Br J Cancer. 1979 Jan;39(1):1-7. doi: 10.1038/bjc.1979.1.
Breast-cancer incidence and mortality rates in different countries were found to be correlated with height, weight and age at menarche, all of which have been identified as risk factors in cohort or case-control studies of breast cancer. There were, however, correlations with total fat and animal protein consumption per capita even after controlling for the 3 anthropometric variables. This suggests that, while some of the effects of diet on breast-cancer rates may be mediated through effects on these known risk factors, there may be more direct effects as well.
研究发现,不同国家的乳腺癌发病率和死亡率与身高、体重以及初潮年龄相关,在乳腺癌队列研究或病例对照研究中,所有这些因素均被确定为风险因素。然而,即便在控制了这三个人体测量变量之后,乳腺癌发病率和死亡率仍与人均总脂肪及动物蛋白摄入量相关。这表明,虽然饮食对乳腺癌发病率的某些影响可能是通过对这些已知风险因素的作用来介导的,但也可能存在更直接的影响。