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1
Photodynamic effect of haematoporphyrin throughout the cell cycle of the human cell line NHIK 3025 cultivated in vitro.血卟啉在体外培养的人细胞系NHIK 3025整个细胞周期中的光动力效应。
Br J Cancer. 1979 Jan;39(1):64-8. doi: 10.1038/bjc.1979.8.
2
Multiplication of human NHIK 3025 cells exposed to porphyrins in combination with light.暴露于卟啉并结合光照的人NHIK 3025细胞的增殖
Br J Cancer. 1981 Sep;44(3):433-9. doi: 10.1038/bjc.1981.202.
3
Photodynamic effects of haematoporphyrin derivative on synchronized and asynchronous cells of different origin.血卟啉衍生物对不同来源同步化和非同步化细胞的光动力效应。
Br J Cancer. 1981 Nov;44(5):717-24. doi: 10.1038/bjc.1981.258.
4
The mechanism of photodynamic inactivation of human cells in vitro in the presence of haematoporphyrin.在血卟啉存在的情况下，体外对人体细胞进行光动力灭活的机制。
Br J Cancer. 1979 Apr;39(4):398-407. doi: 10.1038/bjc.1979.72.
5
Photodynamic action and chromosomal damage: a comparison of haematoporphyrin derivative (HpD) and light with X-irradiation.
Br J Cancer. 1982 Mar;45(3):456-65. doi: 10.1038/bjc.1982.74.
6
Photodynamic inactivation of synchronized human cells in vitro in the presence of hematoporphyrin.
Cancer Res. 1979 Sep;39(9):3735-7.
7
Photodynamic inactivation of cancer cells in vitro. Effect of irradiation temperature and dose fractionation.
Cancer Lett. 1979 May;6(6):331-5. doi: 10.1016/s0304-3835(79)80090-7.
8
Effects of haematoporphyrin derivative and light in combination with hyperthermia on cells in culture.血卟啉衍生物及光联合热疗对培养细胞的影响。
Br J Cancer. 1984 Jul;50(1):85-9. doi: 10.1038/bjc.1984.142.
9
[Comparative study of hematoporphyrin and psoralen effects on fibroblasts after black light irradiation (author's transl)].
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10
A change in the oxygen effect throughout the cell-cycle of human cells of the line NHIK 3025 cultivated in vitro.体外培养的NHIK 3025系人细胞在整个细胞周期中氧效应的变化。
Int J Radiat Biol Relat Stud Phys Chem Med. 1977 Feb;31(2):171-84. doi: 10.1080/09553007714550191.

引用本文的文献

1
Multiplication of human NHIK 3025 cells exposed to porphyrins in combination with light.暴露于卟啉并结合光照的人NHIK 3025细胞的增殖
Br J Cancer. 1981 Sep;44(3):433-9. doi: 10.1038/bjc.1981.202.
2
Porphyrin-sensitized photoinactivation of human cells in vitro.卟啉敏化的人细胞体外光灭活
Am J Pathol. 1982 Nov;109(2):184-92.
3
In vivo biological activity of the components of haematoporphyrin derivative.血卟啉衍生物各成分的体内生物活性。
Br J Cancer. 1982 Apr;45(4):571-81. doi: 10.1038/bjc.1982.94.
4
Photodynamic effects of haematoporphyrin derivative on synchronized and asynchronous cells of different origin.血卟啉衍生物对不同来源同步化和非同步化细胞的光动力效应。
Br J Cancer. 1981 Nov;44(5):717-24. doi: 10.1038/bjc.1981.258.
5
The mechanism of photodynamic inactivation of human cells in vitro in the presence of haematoporphyrin.在血卟啉存在的情况下，体外对人体细胞进行光动力灭活的机制。
Br J Cancer. 1979 Apr;39(4):398-407. doi: 10.1038/bjc.1979.72.

本文引用的文献

1
The mechanism of the photodynamic effect.光动力效应的机制。
J Invest Dermatol. 1959 Feb;32(2, Part 2):233-47.
2
Clonal growth in vitro of human cells with fibroblastic morphology; comparison of growth and genetic characteristics of single epithelioid and fibroblast-like cells from a variety of human organs.具有成纤维细胞形态的人细胞在体外的克隆生长；来自多种人体器官的单个上皮样细胞和成纤维细胞样细胞的生长及遗传特征比较。
J Exp Med. 1957 Jul 1;106(1):145-58. doi: 10.1084/jem.106.1.145.
3
X-ray sensitivity during the cell generation cycle of cultured Chinese hamster cells.培养的中国仓鼠细胞在细胞生成周期中的X射线敏感性。
Radiat Res. 1966 Nov;29(3):450-74.
4
Sensitivity of synchronized Chinese hamster cells to ultraviolet light.同步化中国仓鼠细胞对紫外线的敏感性。
Biophys J. 1969 Sep;9(9):1171-92. doi: 10.1016/S0006-3495(69)86444-1.
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Age responses of cultured mammalian cells to cytotoxic drugs.培养的哺乳动物细胞对细胞毒性药物的年龄反应。
Cancer Res. 1970 May;30(5):1397-408.
6
Variation in sensitivity to heat shock during the cell-cycle of Chinese hamster cells in vitro.体外培养的中国仓鼠细胞在细胞周期中对热休克敏感性的变化。
Int J Radiat Biol Relat Stud Phys Chem Med. 1971;19(5):467-77. doi: 10.1080/09553007114550601.
7
Diagnosis of model choroidal malignant melanoma by hematoporphyrin derivative fluorescence in rabbits.
Invest Ophthalmol. 1974 Apr;13(4):244-55.
8
X-ray inactivation of human cells in tissue culture under aerobic and extremely hypoxic conditions in the presence and absence of TMPN.在有氧和极度缺氧条件下，存在和不存在三甲基吡啶鎓硝酸盐（TMPN）时，组织培养中人类细胞的X射线失活。
Int J Radiat Biol Relat Stud Phys Chem Med. 1973 Sep;24(3):285-96. doi: 10.1080/09553007314551121.
9
Energetics and efficiency of photoinactivation of murine tumor cells containing hematoporphyrin.含血卟啉的小鼠肿瘤细胞光灭活的能量学与效率
Cancer Res. 1976 Jul;36(7 PT 1):2330-3.
10
Hematoporphyrin derivative: a possible aid in the diagnosis and therapy of carcinoma of the bladder.
J Urol. 1976 Feb;115(2):150-1. doi: 10.1016/s0022-5347(17)59108-9.

血卟啉在体外培养的人细胞系NHIK 3025整个细胞周期中的光动力效应。

Photodynamic effect of haematoporphyrin throughout the cell cycle of the human cell line NHIK 3025 cultivated in vitro.

作者信息

Christensen T, Moan J, Wibe E, Oftebro R

出版信息

Br J Cancer. 1979 Jan;39(1):64-8. doi: 10.1038/bjc.1979.8.

DOI:10.1038/bjc.1979.8
PMID:758929
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2009795/
Abstract

Cells from the established cell line NHIK 3025 were synchronized by repeated mitotic selections. Survival of the synchronized cells after treatment with haematoporphyrin and near-UV light was measured by testing the capacity of the cells to form macroscopic colonies. The sensitivity to photodynamic inactivation was small in early G1, late S and G2. The sensitivity increased throughout late G1 and early S to a maximum in mid S. More than a 100-fold variation is found in the survival after 20 min irradiation in the presence of 4 X 10(-4)M haematoporphyrin.

摘要

来自已建立的NHIK 3025细胞系的细胞通过重复的有丝分裂选择进行同步化。用血卟啉和近紫外光处理后，通过测试细胞形成肉眼可见菌落的能力来测量同步化细胞的存活率。在G1早期、S后期和G2期，对光动力失活的敏感性较小。在整个G1后期和S早期，敏感性增加，在S中期达到最大值。在存在4×10(-4)M血卟啉的情况下照射20分钟后，存活率发现有超过100倍的变化。