Sandyk R
NeuroCommunication Research Laboratories, Danbury, CT 06811, USA.
Int J Neurosci. 1995 May;82(1-2):113-25. doi: 10.3109/00207459508994295.
It is now well established that dreaming is a phenomenon associated with REM sleep and that we dream far more than we can recall. Loss of dream recall has been reported in association with cerebral lesions of different sites with predilection to the posterior cerebral hemispheres. Multiple sclerosis (MS) is a chronic neurological disorder characterised by the presence of diffuse pathological lesions affecting cortical, subcortical, and brainstem areas which are implicated in the generation and maintenance of REM sleep as well as dream recall. Although MS is associated with a high incidence of sleep disturbances, little is known about the frequency of dreaming and particularly dream recall in these patients and their association with such features as the course of the disease, extent of neurological deficits, rate of progression, sites of demyelinating plaques on MRI scan, and recovery. In my experience morning dream recall and probably dreaming activity become infrequent with the onset and/or during periods of exacerbation of the disease. The present communication concerns four selected MS patients who experienced alterations in dream content and loss of morning dream recall during the course of the disease. In all patients dream recall was restored, along with improvement in neurological symptoms, following the external application of a series of treatments with weak electromagnetic fields (EMFs). These findings suggest that in MS morning dream recall may decline and cease to occur during the course of the disease. Recurrence of dream recall may be a marker of clinical recovery which can be used to assess neurologic improvement in patients undergoing treatment with experimental treatment modalities.
现在已经充分证实，做梦是一种与快速眼动睡眠相关的现象，而且我们做梦的次数远比我们能够回忆起来的要多。据报道，不同部位的脑部病变，尤其是大脑后半球的病变，会导致梦境回忆丧失。多发性硬化症（MS）是一种慢性神经疾病，其特征是存在弥漫性病理病变，影响皮质、皮质下和脑干区域，这些区域与快速眼动睡眠的产生和维持以及梦境回忆有关。尽管MS与睡眠障碍的高发病率相关，但对于这些患者做梦的频率，尤其是梦境回忆，以及它们与疾病进程、神经功能缺损程度、进展速度、MRI扫描上脱髓鞘斑块的部位和恢复情况等特征之间的关联，我们所知甚少。根据我的经验，随着疾病的发作和/或加重期，早晨的梦境回忆以及可能的做梦活动会变得不常见。本报告涉及四名选定的MS患者，他们在疾病过程中经历了梦境内容的改变和早晨梦境回忆的丧失。在所有患者中，在一系列弱电磁场（EMF）治疗外用后，梦境回忆恢复，同时神经症状也有所改善。这些发现表明，在MS患者中，早晨的梦境回忆可能在疾病过程中下降并停止出现。梦境回忆的恢复可能是临床恢复的一个标志，可用于评估接受实验性治疗方式治疗的患者的神经功能改善情况。
